GI Liver, Biliary, and Pancreatic Disorders

Question 1

Which liver enzyme is considered most specific for hepatocellular damage?

Accepted Answer

ALT (alanine aminotransferase)

Answer

AST (aspartate aminotransferase)

Answer

Alkaline phosphatase

Answer

GGT (gamma-glutamyl transferase)

Question 2

What is the most common cause of acute pancreatitis in the United States?

Accepted Answer

Gallstones

Answer

Chronic alcohol use

Answer

Hypertriglyceridemia

Answer

Medication-induced

Question 3

Which antibody is most characteristic of primary biliary cholangitis (PBC)?

Accepted Answer

Anti-mitochondrial antibody (AMA)

Answer

Anti-smooth muscle antibody (ASMA)

Answer

Anti-nuclear antibody (ANA)

Answer

pANCA

Question 4

In hepatic encephalopathy, which neurotoxic substance primarily accumulates due to failed hepatic clearance?

Accepted Answer

Ammonia

Answer

Bilirubin

Answer

Urea

Answer

Creatinine

Question 5

Which is the most common primary malignancy of the liver in adults?

Accepted Answer

Hepatocellular carcinoma (HCC)

Answer

Cholangiocarcinoma

Answer

Angiosarcoma

Answer

Hepatoblastoma

Question 6

On MRCP or ERCP, primary sclerosing cholangitis (PSC) characteristically shows which finding in the bile ducts?

Accepted Answer

A beaded, multifocal stricture pattern

Answer

Smooth diffuse dilation of the common bile duct

Answer

Single dominant stricture at the hilum

Answer

Intrahepatic gallstones

Question 7

The MELD score used to prioritize liver transplant candidates incorporates which combination of laboratory values?

Accepted Answer

Bilirubin, INR, and creatinine

Answer

ALT, AST, and albumin

Answer

Bilirubin, albumin, and prothrombin time

Answer

AST, ALT, and platelet count