FREE NBDE Oral Pathology Diagnosis Questions and Answers

Question 1

A 45-year-old male presents with a solitary, firm, non-tender, dome-shaped nodule on the buccal mucosa, approximately 1 cm in diameter.
The lesion has been present for several months and the patient reports occasionally biting it.
Histopathological examination reveals a well-circumscribed proliferation of fibroblasts and collagen fibers, often with a myxoid stroma and inflammatory cells.
What is the most likely diagnosis?

Accepted Answer

Fibroma

Answer

Lipoma

Answer

Granular cell tumor

Answer

Neurofibroma

Question 2

Which of the following conditions is characterized by a 'cobblestone' appearance of the oral mucosa, often associated with diffuse gingival enlargement and linear ulcerations, and may also involve the gastrointestinal tract?

Accepted Answer

Crohn's disease

Answer

Lichen planus

Answer

Pemphigus vulgaris

Answer

Erythema multiforme

Question 3

A 60-year-old heavy smoker and alcohol consumer presents with a persistent, non-healing ulcer on the lateral border of the tongue that has been present for 3 months. The lesion is indurated and exhibits exophytic growth. Lymphadenopathy is noted in the ipsilateral cervical region. Which diagnostic procedure is most critical for confirming the suspected diagnosis?

Accepted Answer

Incisional biopsy

Answer

Exfoliative cytology

Answer

Fine needle aspiration of the lymph node

Answer

Panoramic radiograph

Question 4

Which developmental cyst is typically found in the anterior maxilla, often between the roots of the maxillary central incisors, and is lined by stratified squamous epithelium or pseudostratified columnar epithelium?

Accepted Answer

Nasopalatine duct cyst

Answer

Odontogenic keratocyst

Answer

Lateral periodontal cyst

Answer

Radicular cyst

Question 5

A 30-year-old female presents with recurrent, painful, small, shallow ulcers with an erythematous halo on the non-keratinized oral mucosa (buccal mucosa, labial mucosa, soft palate). The lesions heal within 7-10 days without scarring. She reports a history of similar episodes since adolescence. What is the most probable diagnosis?

Accepted Answer

Recurrent aphthous stomatitis (minor type)

Answer

Herpes labialis

Answer

Pemphigoid

Answer

Erythema multiforme

Question 6

A panoramic radiograph of a 55-year-old asymptomatic patient reveals a well-defined, unilocular radiolucency with a sclerotic border in the posterior mandible, inferior to the mandibular canal. The lesion does not appear to be associated with any teeth. What is the most likely diagnosis?

Accepted Answer

Stafne bone defect (Stafne defect)

Answer

Ameloblastoma

Answer

Dentigerous cyst

Answer

Residual cyst