FREE HSR Institutional Review Board (IRB) Processes Questions and Answers

Question 1

What is the primary role of the Institutional Review Board (IRB)?

Accepted Answer

To review and approve research involving human participants

Answer

To fund research studies

Answer

To recruit participants for research

Answer

To conduct data analysis for research

Question 2

Who is responsible for submitting a research proposal to the IRB?

Accepted Answer

The researcher or principal investigator

Answer

The study participants

Answer

The IRB committee members

Answer

The research sponsor

Question 3

What are the key factors the IRB considers when reviewing a research proposal?

Accepted Answer

The risks to participants, informed consent, and potential benefits

Answer

The availability of funding

Answer

The researcher's qualifications

Answer

The location of the research site

Question 4

What is the purpose of obtaining informed consent from participants in research?

Accepted Answer

To inform participants of the study’s risks, benefits, and their rights

Answer

To comply with legal requirements

Answer

To make the research study appear more ethical

Answer

To reduce the cost of research

Question 5

How often should the IRB review a research study once it has been approved?

Accepted Answer

Every 6 months or annually

Answer

Once, at the beginning of the study

Answer

Only if there is a complaint from participants

Answer

Once, before the study begins and again after it ends

Question 6

What must be done if a research study's protocols change after IRB approval?

Accepted Answer

The changes must be reported to the IRB for approval before implementation

Answer

The researcher can implement the changes without notifying the IRB

Answer

Changes do not need IRB approval as long as the research is not impacted

Answer

The changes must be implemented immediately to ensure research continuity

Question 7

What is the significance of the IRB's role in protecting vulnerable populations in research?

Accepted Answer

To ensure that vulnerable populations are not exploited and are protected from harm

Answer

To reduce the costs associated with vulnerable participants

Answer

To ensure that researchers recruit a higher number of participants from vulnerable populations

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To minimize the time required for participant recruitment

Question 8

How should an investigator handle a situation where the IRB denies approval for a study?

Accepted Answer

Revise the research proposal based on the IRB's feedback and resubmit for approval

Answer

Ignore the IRB's concerns and proceed with the study

Answer

Appeal the decision to the research sponsor

Answer

Proceed with the study if the researcher believes it is ethical

Question 9

What is the IRB's responsibility regarding a researcher's potential conflict of interest?

Accepted Answer

To ensure that any conflicts of interest are disclosed and do not affect the study’s integrity

Answer

To allow the researcher to proceed without any intervention if they disclose the conflict

Answer

To remove the researcher from the study if a conflict is identified

Answer

To ignore conflicts of interest as long as participants are informed