FREE CAADC Pharmacology and MAT Questions and Answers

Question 1

Buprenorphine is referred to as a partial opioid agonist. What does this mean in the context of treating Opioid Use Disorder (OUD)?

Accepted Answer

It activates opioid receptors to a lesser degree than full agonists, creating a ceiling effect.

Answer

It completely blocks opioid receptors, preventing any opioid effect.

Answer

It only works when combined with naloxone.

Answer

It is a short-acting medication that must be taken several times a day.

Question 2

A client with Alcohol Use Disorder (AUD) is prescribed naltrexone. What is the primary mechanism of action by which this medication supports recovery?

Accepted Answer

It reduces the rewarding effects of alcohol and helps decrease cravings.

Answer

It causes a severe physical reaction (e.g., nausea, vomiting) if alcohol is consumed.

Answer

It stabilizes brain chemistry by mimicking the effects of alcohol.

Answer

It treats underlying anxiety that often co-occurs with AUD.

Question 3

Chronic, heavy use of stimulants like methamphetamine primarily impacts which two neurotransmitter systems, leading to significant mood disturbances and anhedonia during withdrawal?

Accepted Answer

Dopamine and Norepinephrine

Answer

GABA and Glutamate

Answer

Serotonin and Acetylcholine

Answer

Endorphins and Anandamide

Question 4

A client has been taking high doses of alprazolam (Xanax) daily for over a year and wants to stop. What is the most significant risk of abrupt cessation, and what is the recommended clinical approach?

Accepted Answer

Risk of life-threatening seizures; recommend a slow, medically supervised taper.

Answer

Risk of severe depression; recommend immediate antidepressant medication.

Answer

Risk of rebound anxiety; recommend non-addictive anxiety medication.

Answer

Risk of cardiac arrest; recommend inpatient hospitalization with cardiac monitoring.

Question 5

Which medication for Opioid Use Disorder requires dispensing from a federally regulated Opioid Treatment Program (OTP) and has a significant risk of QT interval prolongation?

Accepted Answer

Methadone

Answer

Buprenorphine

Answer

Naltrexone

Answer

Disulfiram

Question 6

Disulfiram (Antabuse) is a medication used for Alcohol Use Disorder that works through which of the following mechanisms?

Accepted Answer

Inhibiting an enzyme, leading to a toxic reaction when alcohol is ingested.

Answer

Blocking opioid receptors to reduce alcohol cravings.

Answer

Modulating glutamate transmission to reduce withdrawal symptoms.

Answer

Acting as a partial agonist at nicotinic receptors.