FRCR FRCR Clinical Oncology 3

Question 1

In the 4Rs of radiobiology, which process refers to cells moving from a radiation-resistant phase to a more sensitive phase?

Accepted Answer

Reassortment (redistribution)

Answer

Repair

Answer

Repopulation

Answer

Reoxygenation

Question 2

Palliative radiotherapy for painful bone metastases most commonly uses which fractionation schedule in the US?

Accepted Answer

Single fraction 8 Gy

Answer

30 Gy in 10 fractions

Answer

20 Gy in 5 fractions

Answer

45 Gy in 25 fractions

Question 3

Which imaging modality is most commonly used for radiation therapy treatment planning?

Accepted Answer

CT simulation

Answer

MRI

Answer

PET-CT

Answer

Fluoroscopy

Question 4

The Gleason grading system is used to characterize which malignancy treated with radiotherapy?

Accepted Answer

Prostate cancer

Answer

Bladder cancer

Answer

Rectal cancer

Answer

Cervical cancer

Question 5

Radiation-induced spinal cord injury (myelopathy) is most closely associated with exceeding which dose constraint?

Accepted Answer

45–50 Gy in conventional fractionation

Answer

30 Gy in 10 fractions

Answer

20 Gy single fraction

Answer

60 Gy in 30 fractions

Question 6

Which radionuclide therapy is FDA-approved for metastatic castration-resistant prostate cancer with bone metastases?

Accepted Answer

Radium-223 dichloride (Xofigo)

Answer

Lutetium-177 DOTATATE

Answer

Iodine-131

Answer

Yttrium-90 microspheres