FPGEE Pharmaceutics 2

Question 1

Which dissolution model describes drug release that is proportional to the square root of time?

Accepted Answer

Higuchi model

Answer

Zero-order model

Answer

First-order model

Answer

Korsmeyer-Peppas model

Question 2

A tablet formulation requires a disintegrant that swells rapidly upon contact with water. Which excipient is MOST appropriate?

Accepted Answer

Sodium starch glycolate

Answer

Magnesium stearate

Answer

Microcrystalline cellulose

Answer

Talc

Question 3

What is the primary purpose of an enteric coating on an oral solid dosage form?

Accepted Answer

Prevent drug release in the stomach

Answer

Improve taste masking

Answer

Increase drug dissolution rate

Answer

Protect the drug from light

Question 4

In a parenteral emulsion intended for intravenous administration, the droplet size of the dispersed phase must not exceed:

Accepted Answer

5 microns

Answer

10 microns

Answer

1 micron

Answer

0.5 microns

Question 5

Which factor primarily determines whether a drug is classified as BCS Class I?

Accepted Answer

High solubility and high permeability

Answer

Low solubility and high permeability

Answer

High solubility and low permeability

Answer

Low solubility and low permeability

Question 6

The van't Hoff equation is used in pharmacy to calculate:

Accepted Answer

Osmotic pressure of a solution

Answer

Rate of drug degradation

Answer

Partition coefficient

Answer

Viscosity of a suspension

Question 7

A cream formulation is classified as an oil-in-water (O/W) emulsion. Which of the following is a characteristic of this type?

Accepted Answer

It is water-washable

Answer

It leaves an occlusive film

Answer

It is miscible with oils

Answer

It does not contain an emulsifying agent