EMS Pharmacology & Drug Administration 2 — Questions and Answers
Question 1: Which drug class does adenosine belong to, and what is its primary EMS use?
- Beta-blocker used for hypertension
- Antiarrhythmic used to convert supraventricular tachycardia (SVT) (Correct answer)
- Calcium channel blocker used for chest pain
- Diuretic used for pulmonary edema
Correct answer: Antiarrhythmic used to convert supraventricular tachycardia (SVT)
Adenosine is an endogenous antiarrhythmic that temporarily blocks AV node conduction to terminate SVT.
Question 2: A patient is experiencing an anaphylactic reaction. The standard adult dose of epinephrine 1:1,000 given IM is:
- 0.1 mg
- 0.3 mg (Correct answer)
- 0.5 mg
- 1.0 mg
Correct answer: 0.3 mg
The standard adult IM dose for anaphylaxis is 0.3 mg of epinephrine 1:1,000 into the anterolateral thigh.
Question 3: What is the mechanism of action of naloxone (Narcan)?
- It metabolizes opioids in the bloodstream
- It competitively blocks opioid receptors (Correct answer)
- It stimulates respiratory drive directly
- It binds to GABA receptors to reverse CNS depression
Correct answer: It competitively blocks opioid receptors
Naloxone works by competitively binding and blocking opioid receptors, reversing opioid-induced CNS and respiratory depression.
Question 4: When administering nitroglycerin sublingually, which vital sign must be checked BEFORE each dose?
- Heart rate
- Respiratory rate
- Blood pressure (Correct answer)
- Oxygen saturation
Correct answer: Blood pressure
Blood pressure must be checked before each nitroglycerin dose because it causes vasodilation and can precipitate dangerous hypotension.
Question 5: A 70 kg patient needs a dopamine infusion at 5 mcg/kg/min. The bag contains 400 mg in 250 mL. What is the drip rate in mL/hr?
- 13.1 mL/hr (Correct answer)
- 26.3 mL/hr
- 52.5 mL/hr
- 105 mL/hr
Correct answer: 13.1 mL/hr
Dose = 5 mcg/kg/min × 70 kg = 350 mcg/min; concentration = 400,000 mcg/250 mL = 1,600 mcg/mL; rate = 350/1,600 × 60 min = 13.1 mL/hr.
Question 6: Which of the following is an absolute contraindication to morphine sulfate in EMS?
- Patient has a history of kidney stones
- Patient has a systolic BP below 90 mmHg (Correct answer)
- Patient is over 65 years old
- Patient has mild nausea
Correct answer: Patient has a systolic BP below 90 mmHg
Morphine causes vasodilation and can worsen hypotension; a systolic BP below 90 mmHg is an absolute contraindication.
Question 7: Activated charcoal is CONTRAINDICATED in which of the following ingestion scenarios?
- Acetaminophen overdose within 1 hour
- Aspirin overdose within 2 hours
- Caustic (acid or alkali) ingestion (Correct answer)
- Benzodiazepine overdose
Correct answer: Caustic (acid or alkali) ingestion
Activated charcoal is contraindicated for caustic ingestion because it does not adsorb these substances and obscures endoscopic evaluation.
Which drug class does adenosine belong to, and what is its primary EMS use?