Clinical Pathology and Diagnostics Flashcards
7 cards from real DVM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Clinical Pathology and Diagnostics flashcards as text
A cow presents with milk fever. Which serum electrolyte abnormality is expected?
Answer: Hypocalcemia
Milk fever (parturient paresis) is caused by hypocalcemia due to the sudden calcium demand at the onset of lactation exceeding homeostatic mechanisms.
A dog with splenic hemangiosarcoma is presented. Which CBC finding would most strongly support active hemorrhage into the abdominal cavity?
Answer: Regenerative anemia with thrombocytopenia and schistocytes
Regenerative anemia with thrombocytopenia and red cell fragmentation (schistocytes) suggests hemorrhage combined with microangiopathic changes, common with hemangiosarcoma.
An ACTH stimulation test in a dog yields a pre-cortisol of 2 µg/dL and post-cortisol of 2.5 µg/dL. What does this confirm?
Answer: Hypoadrenocorticism
A blunted cortisol response to ACTH (both pre- and post-stimulation values low or below normal) confirms hypoadrenocorticism (Addison's disease).
Which stain is most appropriate for identifying lipid droplets in hepatocytes on a liver fine-needle aspirate?
Answer: Oil Red O on air-dried unfixed sample
Oil Red O stains neutral lipids red/orange and must be applied to unfixed, air-dried smears before lipids dissolve during routine processing.
A feline patient has a packed cell volume of 55% and a concurrent low erythropoietin level. What is the most likely underlying cause?
Answer: Primary erythrocytosis (polycythemia vera)
Primary erythrocytosis (polycythemia vera) is a myeloproliferative disorder where erythropoietin is suppressed due to autonomous RBC overproduction.
A dog's urine protein:creatinine (UPC) ratio is 4.2 with no active sediment. What is the most likely diagnosis?
Answer: Glomerulonephropathy
A UPC ratio above 2.0 with inactive sediment and no lower urinary tract disease strongly suggests glomerulonephropathy as the source of proteinuria.
A caprine blood smear shows Heinz bodies on new methylene blue stain. Which toxin is most commonly responsible in goats?
Answer: Copper
Copper toxicity in small ruminants causes oxidative damage to hemoglobin, forming Heinz bodies and leading to intravascular hemolytic crisis.