CWCA CWCA Advanced Wound Therapies 2 — Questions and Answers
Question 1: Ultrasonic debridement (low-frequency ultrasound) is beneficial in chronic wound care because it:
- Creates surgical-level excision of all wound layers
- Disrupts biofilm and stimulates healing without damaging viable tissue (Correct answer)
- Eliminates the need for any other debridement method
- Works only on superficial epidermal wounds
Correct answer: Disrupts biofilm and stimulates healing without damaging viable tissue
Low-frequency ultrasound uses cavitation and acoustic streaming to disrupt biofilm and enhance cellular activity while preserving viable granulation tissue.
Question 2: Collagen-based wound dressings support healing by:
- Creating a waterproof barrier to prevent moisture loss
- Providing a scaffold that attracts fibroblasts and supports tissue regeneration (Correct answer)
- Delivering topical antibiotics to the wound bed
- Absorbing large volumes of wound exudate only
Correct answer: Providing a scaffold that attracts fibroblasts and supports tissue regeneration
Collagen dressings provide a biocompatible matrix that promotes fibroblast migration, collagen synthesis, and organized tissue regeneration.
Question 3: Growth factor therapy in wound care, such as becaplermin (Regranex), is primarily indicated for:
- Venous leg ulcers with heavy exudate
- Diabetic neuropathic foot ulcers not responding to standard care (Correct answer)
- Pressure injuries stage 1 and 2
- Burns covering more than 20% total body surface area
Correct answer: Diabetic neuropathic foot ulcers not responding to standard care
Becaplermin (PDGF) is FDA-approved specifically for chronic diabetic neuropathic ulcers that have adequate blood supply but are not healing with standard therapy.
Question 4: Maggot debridement therapy (MDT) is most effective for wounds with:
- Excessive granulation tissue
- Slough and necrotic tissue in a chronic wound (Correct answer)
- Heavy purulent exudate from active infection
- Tunneling or undermining deeper than 2 cm
Correct answer: Slough and necrotic tissue in a chronic wound
Medicinal larvae selectively digest necrotic and sloughy tissue while secreting antimicrobial compounds, making MDT effective for chronic wounds with devitalized tissue.
Question 5: Platelet-Rich Plasma (PRP) therapy promotes wound healing by:
- Suppressing the inflammatory phase of wound healing
- Concentrating growth factors from the patient's own blood to stimulate tissue repair (Correct answer)
- Providing synthetic scaffolding to replace lost dermis
- Delivering systemic antibiotics to the wound site
Correct answer: Concentrating growth factors from the patient's own blood to stimulate tissue repair
PRP concentrates PDGF, TGF-β, VEGF, and other autologous growth factors that activate fibroblasts, endothelial cells, and keratinocytes to accelerate healing.
Question 6: When applying NPWT to a wound near a blood vessel or organ, which foam interface material should be used?
- Black polyurethane foam
- White polyvinyl alcohol (PVA) foam (Correct answer)
- Standard gauze filler
- Hydrocolloid base layer
Correct answer: White polyvinyl alcohol (PVA) foam
White PVA foam is denser and less aggressive than black polyurethane foam, making it safer near fragile structures such as blood vessels, tendons, and organs.
Ultrasonic debridement (low-frequency ultrasound) is beneficial in chronic wound care because it: