CTA Study Guide 2026
Everything you need to pass the CTA exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 CTA Exam Format at a Glance
📚 CTA Topics to Study (69)
✍️ Sample CTA Questions & Answers
1. What is a confidence interval (CI) used for in clinical trial reporting?
A confidence interval provides a range of plausible values for the true treatment effect, with a 95% CI meaning the true value falls within that range 95% of the time.
2. A CTA notices that the same site coordinator has been entering data for multiple subjects simultaneously using different browser tabs in the eCRF. What concern does this raise?
Entering data for multiple subjects simultaneously across browser tabs increases the risk of entering the wrong data for the wrong subject, compromising data integrity.
3. What is the purpose of a Protocol Deviation Report (PDR) in a clinical trial?
A PDR documents and communicates any departure from the approved protocol to the sponsor and, when required, to the IRB/ethics committee.
4. During a protocol review, a CTA notices that the washout period between study treatments appears too short to eliminate carryover effects. What should the CTA do?
The CTA should document the concern and escalate to the appropriate clinical team members for scientific and medical review.
5. When a CTA performs source data verification (SDV), what is being confirmed?
SDV confirms that data entered into the CRF is consistent, complete, and accurate when compared to the original source records.
6. What is the Medical Dictionary for Regulatory Activities (MedDRA)?
MedDRA is a globally harmonized, standardized medical terminology used by regulatory authorities and the pharmaceutical industry to code clinical data, including adverse events, in a consistent manner.