CSPT Environmental Monitoring and Testing 5

Question 1

A pharmacy installs a new BSC (biological safety cabinet) in the buffer room. Before use for sterile compounding, which certification must be completed first?

Accepted Answer

Certification per NSF/ANSI 49 by a qualified certifier

Answer

A new BSC must be certified per NSF/ANSI 49 by a qualified certifier to confirm HEPA filter integrity, airflow velocity, and containment before it can be used for compounding.

Question 2

When collecting a contact plate sample from a gloved fingertip, the technician should apply the plate to the fingertip with:

Accepted Answer

Light, consistent pressure for approximately 5–10 seconds per finger

Answer

Consistent, moderate pressure for 5–10 seconds per finger ensures adequate contact between the agar and the glove surface for reliable microbial recovery.

Question 3

A cleanroom's HEPA filter is found to have a pinhole leak during DOP (dispersed oil particulate) testing. What is the appropriate response?

Accepted Answer

Repair or replace the filter, then re-certify before resuming compounding

Answer

A compromised HEPA filter must be repaired or replaced and the area re-certified before compounding can safely resume to ensure ISO classification is maintained.

Question 4

What does a non-viable particle count measure in a sterile compounding environment?

Accepted Answer

The total number of particles of specified sizes per cubic meter regardless of viability

Answer

Non-viable particle counters measure the total number of airborne particles (both living and non-living) of specified sizes to confirm ISO classification is maintained.

Question 5

Which of the following personnel behaviors has the GREATEST impact on viable particle counts in an ISO 5 PEC?

Accepted Answer

Excessive movement and talking during compounding

Answer

Excessive movement and talking generate significant particle shedding from personnel, which is the primary source of viable contamination in cleanroom environments.

CSPT - Compounded Sterile Preparation Technician Practice Test

CSPT - Compounded Sterile Preparation Technician Practice Test

CSPT Environmental Monitoring and Testing 5