CSPT CSPT - Compounded Sterile Preparation Technician Infection Control and Microbiology Questions and Answers 5

Question 1

Which hand hygiene technique is required immediately before donning sterile gloves for compounding Category 2 CSPs according to USP <797>?

Accepted Answer

Performing a surgical hand scrub or antiseptic hand rub for at least 30 seconds followed by a 30-second drying period

Answer

USP <797> requires a thorough hand-and-arm wash followed by an antiseptic hand rub before sterile gloving to minimize bioburden introduction.

Question 2

What is the role of the depyrogenation oven (dry heat oven) in sterile compounding as it relates to infection control?

Accepted Answer

It destroys bacterial endotoxins on glassware using temperatures of 250°C or higher

Answer

Dry heat depyrogenation at ≥250°C for validated time periods destroys pyrogens (endotoxins) on heat-stable items such as glass vials and syringes.

Question 3

A surface contact plate used for environmental monitoring in a cleanroom returns a count of 12 CFU on the ISO 7 anteroom floor. Which conclusion is MOST appropriate?

Accepted Answer

The result exceeds the USP <797> action level for ISO 7 surfaces and corrective action is required

Answer

USP <797> sets action levels for surface monitoring; counts exceeding the threshold for the ISO class zone require investigation and corrective action.

Question 4

Which personal protective equipment (PPE) item must be sterile when used for compounding Category 2 CSPs in an ISO 5 direct compounding area?

Accepted Answer

Sterile gloves

Answer

Sterile gloves are the only PPE component that must be sterile, as they directly contact critical sites; other garbing items are non-shed but not sterile.

Question 5

Biofilm formation in water systems used for compounding poses a significant infection control risk primarily because biofilms:

Accepted Answer

Protect embedded microorganisms from disinfection and can continuously shed viable organisms into the water supply

Answer

Biofilms create a protective extracellular matrix that shields bacteria from disinfectants and antimicrobials, allowing continuous microbial shedding into water used for compounding.

CSPT - Compounded Sterile Preparation Technician Practice Test

CSPT - Compounded Sterile Preparation Technician Practice Test

CSPT CSPT - Compounded Sterile Preparation Technician Infection Control and Microbiology Questions and Answers 5