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Pharmacoeconomics & Reimbursement Flashcards

7 cards from real CSP practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

Read the first 7 Pharmacoeconomics & Reimbursement flashcards as text
  1. Specialty drug A costs $60,000 more than drug B and yields 1.5 additional QALYs. What is the ICER of A versus B?

    Answer: $40,000 per QALY

    ICER = incremental cost / incremental effect = $60,000 / 1.5 QALYs = $40,000 per QALY.

  2. Two biosimilar products have demonstrated equivalent efficacy and safety. Which pharmacoeconomic analysis is most appropriate to choose between them?

    Answer: Cost-minimization analysis

    When outcomes are proven equivalent, only costs need comparison, so cost-minimization analysis applies.

  3. A health system values both the costs of a hepatitis C program and the avoided liver transplants in dollars. Which analysis is this?

    Answer: Cost-benefit analysis

    Cost-benefit analysis expresses both inputs and outcomes in monetary units, allowing a net benefit or benefit-to-cost ratio.

  4. A new therapy is both less costly and more effective than the current standard. How is it described on the cost-effectiveness plane?

    Answer: Dominant

    An option that costs less and produces better outcomes dominates the comparator, so no ICER needs calculating.

  5. A 10-year model of a gene therapy reduces the present value of future costs and health outcomes, commonly at 3% per year. What is this practice called?

    Answer: Discounting

    Discounting reflects time preference by converting future costs and outcomes to present value, typically at about 3% annually in US analyses.

  6. A modeler draws all input parameters at once from probability distributions over 10,000 Monte Carlo iterations. Which technique is this?

    Answer: Probabilistic sensitivity analysis

    Probabilistic sensitivity analysis varies all uncertain parameters at once using distributions and often produces cost-effectiveness acceptability curves.

  7. What is the main purpose of a budget impact analysis that a health plan requests before adding a new specialty drug?

    Answer: Estimate the financial effect of adoption on that plan's budget over a short time horizon

    Budget impact analysis estimates the affordability of adopting a therapy for a specific payer population, usually over 1 to 5 years.