CSMLS Clinical Chemistry Procedures Questions and Answers

Question 1

A patient's blood gas results on room air are: pH 7.25, pCO2 60 mmHg, HCO3- 24 mmol/L. Which of the following conditions is most consistent with these findings?

Accepted Answer

Respiratory acidosis

Answer

Metabolic acidosis

Answer

Respiratory alkalosis

Answer

Metabolic alkalosis

Question 2

A tech runs a quality control for creatinine and the result is 2 standard deviations above the mean. According to Westgard rules, what is the most appropriate first step?

Accepted Answer

Repeat the control on the same vial.

Answer

Report patient results and document the QC deviation.

Answer

Recalibrate the instrument immediately.

Answer

Open a new vial of control and repeat the measurement.

Question 3

Which of the following enzymes is most specific for assessing acute pancreatitis?

Accepted Answer

Lipase (LPS)

Answer

Alanine aminotransferase (ALT)

Answer

Amylase (AMY)

Answer

Creatine kinase (CK)

Question 4

A patient sample for electrolyte analysis is noted to be severely hemolyzed. Which analyte would be most significantly falsely elevated?

Accepted Answer

Potassium (K+)

Answer

Sodium (Na+)

Answer

Chloride (Cl-)

Answer

Bicarbonate (HCO3-)

Question 5

An Oral Glucose Tolerance Test (OGTT) is performed on a non-pregnant adult. A fasting glucose of 6.8 mmol/L and a 2-hour post-load glucose of 11.5 mmol/L is obtained. According to Canadian Diabetes Association guidelines, this is indicative of:

Accepted Answer

Diabetes mellitus

Answer

Normal glucose tolerance

Answer

Impaired fasting glucose (IFG)

Answer

Impaired glucose tolerance (IGT)

Question 6

What is the principle of the Jaffe reaction for measuring creatinine?

Accepted Answer

Creatinine reacts with picric acid in an alkaline solution to form a red-orange complex.

Answer

An enzymatic reaction using creatininase produces a colored product measured spectrophotometrically.

Answer

Creatinine is measured directly using an ion-selective electrode.

Answer

Urease converts urea to ammonia, and the resulting change in conductivity is measured.

A patient's blood gas results on room air are: pH 7.25, pCO2 60 mmHg, HCO3- 24 mmol/L.Which of the following conditions is most consistent with these findings?

A patient's blood gas results on room air are: pH 7.25, pCO2 60 mmHg, HCO3- 24 mmol/L.
Which of the following conditions is most consistent with these findings?