CSMLS Immunology and Serology Flashcards
6 cards from real CSMLS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 CSMLS Immunology and Serology flashcards as text
A titer of 1:320 compared to 1:40 for the same patient indicates:
Answer: Higher antibody concentration in the 1:320 sample
A titer of 1:320 reflects a higher dilution needed to reduce reactivity, indicating a greater concentration of antibody than a titer of 1:40.
Immunofluorescence microscopy uses antibodies conjugated to:
Answer: Fluorescent dyes
Immunofluorescence uses antibodies labeled with fluorescent dyes (fluorochromes) that emit light when excited by specific wavelengths.
Cross-reactivity in serological testing occurs when:
Answer: An antibody reacts with a different but structurally similar antigen
Cross-reactivity occurs when an antibody raised against one antigen also binds to a structurally similar but different antigen, potentially causing false positives.
In flow cytometry, CD4+ and CD8+ T cell counts are used to monitor:
Answer: HIV disease progression and immune status
CD4+ T helper cell counts are used to monitor HIV disease progression and guide antiretroviral therapy decisions.
Which immunoglobulin class is the primary antibody in secretions such as saliva and breast milk?
Answer: IgA
Secretory IgA is the predominant immunoglobulin in mucosal secretions such as saliva, tears, and breast milk, providing local immunity.
A four-fold rise in antibody titer between acute and convalescent serum samples is considered diagnostic of:
Answer: Active or recent infection with the tested pathogen
A four-fold or greater rise in antibody titer between acute and convalescent samples indicates active infection and seroconversion.