Practice Test GeeksCSMLS - Canadian Society for Medical Laboratory Science Practice Test
← All CSMLS Flashcard Decks

CSMLS Immunology and Serology Flashcards

6 cards from real CSMLS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 CSMLS Immunology and Serology flashcards as text

  1. In a direct Coombs (DAT) test, a positive result indicates:

    Answer: Antibodies or complement bound to red blood cells in vivo

    A positive direct antiglobulin test (DAT) indicates that antibodies or complement proteins are already coating the patient's red blood cells in vivo.

  2. Rheumatoid factor (RF) is an autoantibody directed against:

    Answer: The Fc portion of IgG

    Rheumatoid factor is an autoantibody, typically IgM, that targets the Fc region of IgG immunoglobulins.

  3. Which antinuclear antibody (ANA) pattern is most associated with systemic lupus erythematosus (SLE)?

    Answer: Homogeneous (diffuse)

    The homogeneous (diffuse) ANA pattern is most commonly associated with SLE and correlates with anti-dsDNA and anti-histone antibodies.

  4. In a latex agglutination test, the latex particles are coated with:

    Answer: Known antigen or antibody specific for the analyte being tested

    Latex particles are coated with a known antigen or antibody so they agglutinate visibly when the complementary analyte is present in the patient sample.

  5. The VDRL and RPR tests are used to screen for:

    Answer: Syphilis

    The VDRL (Venereal Disease Research Laboratory) and RPR (Rapid Plasma Reagin) are non-treponemal screening tests for syphilis.

  6. Which cell type is the primary producer of antibodies?

    Answer: Plasma cell

    Plasma cells are terminally differentiated B lymphocytes that are the primary producers of antibodies (immunoglobulins).