Antineoplastic and Biologic Therapies Flashcards
6 cards from real CRNI practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Antineoplastic and Biologic Therapies flashcards as text
Which complication is MOST specifically associated with rituximab infusion therapy?
Answer: Tumor lysis syndrome
Rituximab can cause tumor lysis syndrome, particularly in patients with high tumor burden, due to rapid destruction of B-cells.
When priming IV tubing for vesicant chemotherapy administration, what solution should be used?
Answer: Compatible IV fluid without the drug
IV tubing should be primed with compatible IV fluid rather than the chemotherapy drug to avoid waste of expensive medication and reduce exposure risk.
A patient receiving an antineoplastic infusion develops urticaria and wheezing. After stopping the infusion, what is the priority nursing action?
Answer: Administer prescribed emergency medications
Urticaria and wheezing indicate an anaphylactic reaction requiring immediate administration of emergency medications such as epinephrine per standing orders.
Which vascular access device is MOST appropriate for a chemotherapy regimen requiring intermittent infusions over 6 months?
Answer: Implanted port
An implanted port is ideal for intermittent long-term chemotherapy as it provides reliable central venous access with lower infection rates between treatments.
What is the nurse's responsibility regarding hazardous drug spill management during an infusion?
Answer: Activate the spill kit, contain the area, and follow facility protocol
Hazardous drug spills require use of a dedicated spill kit with proper PPE and containment procedures as outlined in facility protocol.
When calculating the BSA-based dose of an antineoplastic agent, which patient measurement MUST be verified immediately before administration?
Answer: Current weight
Body surface area calculations depend on accurate current weight, which must be verified before each treatment cycle as weight changes directly affect dosing.