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Blood Transfusion Flashcards

7 cards from real CRNI practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient receiving packed red blood cells develops flank pain, hypotension, and hemoglobinuria 30 minutes into the transfusion. Which reaction is most likely occurring?

    Answer: Acute hemolytic transfusion reaction

    Acute hemolytic transfusion reaction (AHTR) classically presents with flank pain, hypotension, and hemoglobinuria due to ABO incompatibility causing rapid intravascular hemolysis.

  2. What is the maximum allowable hang time for a unit of packed red blood cells once it leaves the blood bank?

    Answer: 4 hours

    PRBCs must be infused within 4 hours of leaving the blood bank to prevent bacterial proliferation and product deterioration.

  3. A nurse is preparing to administer fresh frozen plasma (FFP). Which of the following is the correct administration filter to use?

    Answer: Standard 170-260 micron blood filter

    All blood products, including FFP, must be administered through a standard 170-260 micron filter to remove clots and cellular debris.

  4. Which blood product is MOST appropriate for a patient with thrombocytopenic purpura who is actively bleeding with a platelet count of 8,000/mcL?

    Answer: Platelet concentrate

    Platelet concentrate is indicated for active bleeding with severe thrombocytopenia (platelet count below 10,000/mcL).

  5. Transfusion-associated circulatory overload (TACO) is best distinguished from TRALI by which clinical feature?

    Answer: Response to diuretics and elevated BNP

    TACO improves with diuretics and is associated with elevated BNP/NT-proBNP, reflecting volume overload rather than the inflammatory mechanism of TRALI.

  6. A patient with a history of IgA deficiency requires a blood transfusion. Which precaution is MOST critical for this patient?

    Answer: Use IgA-deficient or washed blood products

    Patients with IgA deficiency can develop anti-IgA antibodies and are at high risk for severe anaphylactic reactions; IgA-deficient or washed products are required.

  7. Which solution is SAFE to co-infuse in the same IV line as packed red blood cells?

    Answer: Normal saline (0.9% NaCl)

    Only 0.9% normal saline is compatible for co-infusion with PRBCs; dextrose solutions cause hemolysis and lactated Ringer's contains calcium that can cause clotting.