CRM Substance Use Disorders & Addiction Science 1 — Questions and Answers
Question 1: Which of the following best defines physical dependence on a substance?
- A psychological craving with no bodily changes
- The body's adaptation to a substance requiring it to function normally (Correct answer)
- A moral weakness that causes continued drug use
- A temporary reaction to a single high dose
Correct answer: The body's adaptation to a substance requiring it to function normally
Physical dependence occurs when the body adapts to a substance so that removal causes withdrawal symptoms.
Question 2: The biopsychosocial model of addiction emphasizes that substance use disorders result from:
- Biological factors alone
- Psychological factors alone
- Social factors alone
- An interaction of biological, psychological, and social factors (Correct answer)
Correct answer: An interaction of biological, psychological, and social factors
The biopsychosocial model recognizes addiction as a complex condition influenced by biology, psychology, and social environment.
Question 3: Tolerance in substance use disorders means the individual requires:
- Less of the substance to achieve the same effect
- More of the substance to achieve the same effect (Correct answer)
- A different substance to get any effect
- Medical supervision to use the substance safely
Correct answer: More of the substance to achieve the same effect
Tolerance develops when the body adapts to a drug so that increasingly larger doses are needed to produce the original effect.
Question 4: Which neurotransmitter is most commonly associated with the brain's reward pathway in addiction?
- Serotonin
- GABA
- Dopamine (Correct answer)
- Acetylcholine
Correct answer: Dopamine
Dopamine is the primary neurotransmitter involved in the brain's reward and pleasure circuits implicated in addiction.
Question 5: According to the DSM-5, how many criteria must be met for a diagnosis of Severe Substance Use Disorder?
- 2 or more
- 4 or more
- 6 or more (Correct answer)
- 8 or more
Correct answer: 6 or more
The DSM-5 designates Severe SUD when 6 or more of the 11 diagnostic criteria are met within a 12-month period.
Question 6: Which of the following is a hallmark symptom of opioid withdrawal?
- Euphoria and increased energy
- Muscle aches, sweating, and anxiety (Correct answer)
- Seizures and hallucinations
- Hypersomnia and increased appetite
Correct answer: Muscle aches, sweating, and anxiety
Opioid withdrawal commonly presents with muscle aches, sweating, anxiety, nausea, and insomnia.
CRM Substance Use Disorders & Addiction Science 1
Which of the following best defines physical dependence on a substance?