A patient is being assessed for nocturnal hypoventilation. Which study is most definitive to diagnose obesity hypoventilation syndrome (OHS)?
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A
Overnight pulse oximetry alone
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B
Polysomnography with transcutaneous CO2 monitoring
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C
Daytime ABG showing PaCO2 > 45 mmHg with BMI ≥ 30
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D
Chest X-ray with cardiomegaly