Cardiac Arrest Pharmacology Flashcards
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Read the first 7 Cardiac Arrest Pharmacology flashcards as text
What is the recommended dose of calcium chloride (10%) for hyperkalemia-induced cardiac arrest?
Answer: 1,000 mg (10 mL) IV
Calcium chloride 10% solution: 1,000 mg (10 mL) IV is the standard dose for hyperkalemia-associated cardiac arrest to stabilize the myocardium.
A patient develops pulseless electrical activity after receiving a high spinal anesthetic. Which drug mechanism is MOST relevant?
Answer: Epinephrine alpha-1 effect restoring vascular resistance lost from sympathectomy
High spinal anesthesia causes complete sympathectomy; epinephrine's alpha-1 vasoconstriction is critical to restore systemic vascular resistance and coronary perfusion.
Intralipid (20% lipid emulsion) therapy is indicated as a rescue treatment for cardiac arrest caused by which drug toxicity?
Answer: Local anesthetic systemic toxicity (LAST)
20% lipid emulsion (Intralipid) 1.5 mL/kg IV bolus is recommended for local anesthetic systemic toxicity (LAST), acting as a 'lipid sink' to sequester the drug.
When should the first dose of epinephrine be given during a non-shockable cardiac arrest rhythm (PEA/Asystole)?
Answer: As soon as IV/IO access is established
For non-shockable rhythms, epinephrine 1 mg IV/IO should be given as soon as feasible after IV/IO access is established.
A patient converts from VF to a perfusing rhythm after defibrillation. An amiodarone infusion was started during arrest. What is the maintenance infusion rate?
Answer: 1 mg/min for 6 hours, then 0.5 mg/min for 18 hours
After ROSC, amiodarone is infused at 1 mg/min for 6 hours, then 0.5 mg/min for 18 hours (total 1,050 mg over 24 hours).
Which statement about dopamine use in post-cardiac arrest care is MOST accurate?
Answer: Dopamine 5–10 mcg/kg/min may be used for post-ROSC hypotension
Dopamine at 5–10 mcg/kg/min provides beta-1 inotropic and alpha-1 vasopressor effects and is an acceptable option for post-ROSC hemodynamic support.
During CPR, a paramedic suspects hypomagnesemia as the cause of refractory VF. What is the correct magnesium sulfate dose and route?
Answer: 1–2 g IV/IO push over 1–2 minutes
Magnesium sulfate 1–2 g IV/IO administered over 1–2 minutes (push) is the correct dose for hypomagnesemia-induced refractory VF during cardiac arrest.