CPOA Basic Science 4 — Questions and Answers
Question 1: Which refractive error is characterized by the eyeball being too long, causing light to focus in front of the retina?
- Hyperopia
- Myopia (Correct answer)
- Astigmatism
- Presbyopia
Correct answer: Myopia
Myopia (nearsightedness) results from an axially elongated globe or overly curved cornea, causing parallel light rays to converge anterior to the retina.
Question 2: The conjunctiva is classified as which type of tissue?
- Stratified squamous epithelium only
- Columnar epithelium with goblet cells (Correct answer)
- Keratinized epithelium
- Simple squamous epithelium
Correct answer: Columnar epithelium with goblet cells
The conjunctiva is composed of non-keratinized stratified columnar epithelium containing goblet cells that secrete the mucin layer of the tear film.
Question 3: Which portion of the autonomic nervous system causes pupillary constriction (miosis)?
- Sympathetic nervous system
- Parasympathetic nervous system (Correct answer)
- Somatic motor system
- Sensory nervous system
Correct answer: Parasympathetic nervous system
The parasympathetic nervous system, via CN III and the ciliary ganglion, innervates the sphincter pupillae to constrict the pupil.
Question 4: The vitreous humor occupies which space within the eye?
- Between the cornea and iris
- Between the iris and lens
- Behind the lens to the retina (Correct answer)
- Between the sclera and choroid
Correct answer: Behind the lens to the retina
The vitreous humor is the gel-like substance that fills the posterior segment of the eye, from the back of the lens to the retina.
Question 5: A patient with 20/20 vision in one eye and 20/200 in the other who best-corrects to 20/20 in the weaker eye most likely has:
- Strabismus only
- Amblyopia (Correct answer)
- Normal binocular vision
- Presbyopia
Correct answer: Amblyopia
Amblyopia (lazy eye) is reduced best-corrected visual acuity in an eye without detectable organic disease; the vision cannot be fully corrected with glasses alone.
Question 6: The sclera is primarily composed of which structural protein?
- Elastin
- Keratin
- Collagen (Correct answer)
- Fibronectin
Correct answer: Collagen
The sclera is made predominantly of dense, irregularly arranged collagen fibers that provide the eye's rigid white outer shell.
Question 7: Which cells in the retina are the final output neurons that send visual signals to the brain via the optic nerve?
- Bipolar cells
- Horizontal cells
- Ganglion cells (Correct answer)
- Amacrine cells
Correct answer: Ganglion cells
Retinal ganglion cells form the innermost retinal layer; their axons converge at the optic disc and travel through the optic nerve to the brain.
Which refractive error is characterized by the eyeball being too long, causing light to focus in front of the retina?