CPI Infection Control & Prevention 3

Question 1

A Certified Physician Investigator is reviewing a protocol involving bronchoscopy procedures. Which transmission-based precaution is most appropriate during this aerosol-generating procedure?

Accepted Answer

Airborne Precautions

Answer

Bronchoscopy is an aerosol-generating procedure requiring Airborne Precautions, including N95 respirator use and negative-pressure room when feasible.

Question 2

Which regulatory body in the US sets standards for occupational exposure to blood-borne pathogens in research settings?

Accepted Answer

OSHA

Answer

OSHA's Bloodborne Pathogens Standard (29 CFR 1910.1030) mandates employer protections for workers with occupational exposure to blood-borne pathogens.

Question 3

A trial site is conducting a study involving participants with active pulmonary tuberculosis. Staff entering participant rooms should wear at minimum a:

Accepted Answer

N95 filtering facepiece respirator

Answer

An N95 respirator is the minimum respiratory protection required for entering rooms of patients with suspected or confirmed pulmonary TB.

Question 4

Which of the following disinfection methods achieves the HIGHEST level of disinfection short of sterilization?

Accepted Answer

High-level disinfection with glutaraldehyde

Answer

High-level disinfection with glutaraldehyde or other high-level disinfectants destroys all microorganisms except high numbers of bacterial spores.

Question 5

An investigator conducting a vaccine trial must report a cluster of injection-site abscesses in participants. This is BEST classified as a:

Accepted Answer

Serious adverse event requiring expedited reporting

Answer

A cluster of injection-site abscesses is a serious adverse event potentially linked to the investigational product or technique and requires expedited reporting.

(CPI) Certified Physician Investigator Practice Test

(CPI) Certified Physician Investigator Practice Test

CPI Infection Control & Prevention 3