CPhT Drug Classifications 2 — Questions and Answers
Question 1: Which drug classification includes medications like lisinopril and enalapril used to treat hypertension?
- ACE inhibitors (Correct answer)
- ARBs
- Beta-blockers
- Calcium channel blockers
Correct answer: ACE inhibitors
Lisinopril and enalapril are ACE inhibitors that block the angiotensin-converting enzyme to lower blood pressure.
Question 2: Metformin belongs to which drug class for treating type 2 diabetes?
- Sulfonylureas
- Biguanides (Correct answer)
- Thiazolidinediones
- DPP-4 inhibitors
Correct answer: Biguanides
Metformin is a biguanide that decreases hepatic glucose production and improves insulin sensitivity.
Question 3: Which schedule of controlled substances has the highest accepted medical use but also a high potential for abuse?
- Schedule I
- Schedule II (Correct answer)
- Schedule III
- Schedule IV
Correct answer: Schedule II
Schedule II drugs have accepted medical uses but carry the highest abuse potential among those approved for medical use.
Question 4: Fluoxetine (Prozac) belongs to which antidepressant drug class?
- Tricyclic antidepressants
- MAOIs
- SSRIs (Correct answer)
- SNRIs
Correct answer: SSRIs
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin availability in the brain.
Question 5: Drugs classified as proton pump inhibitors (PPIs) work primarily by:
- Neutralizing stomach acid
- Blocking H2 receptors
- Inhibiting the H+/K+ ATPase enzyme (Correct answer)
- Coating the stomach lining
Correct answer: Inhibiting the H+/K+ ATPase enzyme
PPIs irreversibly inhibit the H+/K+ ATPase (proton pump) on gastric parietal cells to reduce acid secretion.
Question 6: Which drug class does warfarin belong to?
- Antiplatelet agents
- Thrombolytics
- Vitamin K antagonists (Correct answer)
- Direct thrombin inhibitors
Correct answer: Vitamin K antagonists
Warfarin is a vitamin K antagonist that inhibits clotting factor synthesis dependent on vitamin K.
Question 7: Albuterol is classified as which type of bronchodilator?
- Long-acting beta-2 agonist
- Short-acting beta-2 agonist (Correct answer)
- Anticholinergic
- Leukotriene modifier
Correct answer: Short-acting beta-2 agonist
Albuterol is a short-acting beta-2 agonist (SABA) used for rapid relief of bronchospasm.
CPhT Drug Classifications 2
Which drug classification includes medications like lisinopril and enalapril used to treat hypertension?