Sepsis and Infectious Disease Emergencies Flashcards
7 cards from real CPEN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Sepsis and Infectious Disease Emergencies flashcards as text
A 5-year-old presents with high fever, drooling, stridor, and tripod positioning. The child appears toxic. Which action is MOST appropriate?
Answer: Keep the child calm, call anesthesia/ENT, prepare for emergency airway
In suspected epiglottitis, airway stability is paramount; agitating the child or attempting examination can precipitate complete obstruction — immediate expert airway management is required.
Which antibiotic combination is recommended as empiric therapy for a neonate (< 28 days) with suspected sepsis without a focal source?
Answer: Ampicillin and gentamicin
Ampicillin plus gentamicin provides coverage for GBS, Listeria monocytogenes, and gram-negative organisms that are the most common neonatal pathogens.
A 9-year-old with septic shock is on norepinephrine and epinephrine infusions but remains hypotensive. Bedside echocardiography shows severely depressed LV function. Which additional agent is MOST appropriate?
Answer: Add milrinone
Milrinone, a phosphodiesterase-3 inhibitor, improves cardiac contractility and reduces afterload, making it appropriate for septic shock with significant myocardial dysfunction.
Which clinical feature BEST distinguishes Kawasaki disease from sepsis in a febrile child?
Answer: Fever lasting more than 5 days with conjunctivitis, oral changes, rash, and extremity changes
Kawasaki disease is defined by fever ≥5 days plus at least 4 of 5 classic features (conjunctivitis, oral changes, rash, extremity changes, cervical lymphadenopathy), differentiating it from sepsis.
A 12-year-old returns from a camping trip with fever, headache, myalgias, and a macular rash starting on the wrists and ankles spreading centrally. Which treatment should be initiated IMMEDIATELY?
Answer: Doxycycline
Rocky Mountain Spotted Fever (RMSF) is treated with doxycycline in all age groups, including children, and delay in treatment significantly increases mortality.
A 2-year-old with sepsis has a serum glucose of 38 mg/dL. Which dextrose concentration and dose is MOST appropriate for IV correction?
Answer: D10W 5 mL/kg IV
D10W at 5 mL/kg (providing 0.5 g/kg glucose) is the standard pediatric hypoglycemia correction dose; higher concentrations risk vascular injury and osmotic shifts.
During the management of a child with meningococcal sepsis, the nurse notes new onset of unequal pupils and posturing. The MOST immediate intervention is:
Answer: Administer mannitol 0.5-1 g/kg IV and prepare for possible intubation
Unequal pupils and posturing indicate herniation or impending herniation; hyperosmolar therapy with mannitol and preparation for intubation to control ICP are the priority responses.