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CPEN Toxicology and Poisoning Emergencies Flashcards

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  1. A 3-year-old ingested iron supplement tablets. Which early clinical sign is MOST associated with iron toxicity in the gastrointestinal phase?

    Answer: Hematemesis and bloody diarrhea

    Iron is directly corrosive to the GI tract, causing hematemesis, bloody diarrhea, and abdominal pain in the initial GI phase of toxicity.

  2. Which antidote is indicated for severe iron poisoning in a pediatric patient?

    Answer: Deferoxamine

    Deferoxamine chelates free iron in the blood, forming ferrioxamine which is excreted renally, and is the antidote for severe iron toxicity.

  3. A teenager presents with altered mental status, hyperthermia, tachycardia, and mydriasis after ingesting an unknown substance. These findings are MOST consistent with which toxidrome?

    Answer: Sympathomimetic

    Sympathomimetic toxidrome is characterized by hyperthermia, tachycardia, hypertension, mydriasis, and agitation due to excess catecholamine activity.

  4. A 5-year-old is brought in after ingesting a button battery. Which complication is the MOST serious concern if the battery is lodged in the esophagus?

    Answer: Esophageal perforation from liquefactive necrosis

    Button batteries lodged in the esophagus generate hydroxide ions via electrical current, causing rapid liquefactive necrosis that can perforate the esophagus within 2 hours.

  5. An 8-year-old ingested a large amount of acetaminophen 6 hours ago. The MOST important laboratory test to guide antidote therapy at this time is:

    Answer: Serum acetaminophen level plotted on the Rumack-Matthew nomogram

    The serum acetaminophen level drawn 4 or more hours post-ingestion and plotted on the Rumack-Matthew nomogram determines the risk of hepatotoxicity and the need for N-acetylcysteine.

  6. A 2-year-old presents with a serum ethanol level of 80 mg/dL after ingesting mouthwash. Which complication requires PRIORITY monitoring in young children with ethanol ingestion?

    Answer: Hypoglycemia

    Young children are at high risk for ethanol-induced hypoglycemia because they have limited glycogen stores and ethanol inhibits gluconeogenesis.

  7. Which of the following household products contains hydrocarbons and poses the GREATEST risk of aspiration pneumonitis in children?

    Answer: Gasoline or lamp oil

    Low-viscosity hydrocarbons like gasoline and lamp oil have a high aspiration potential due to their low surface tension, spreading easily into the lungs and causing pneumonitis.

CPEN Toxicology and Poisoning Emergencies Flashcards โ€” CPEN Study Cards with Answers