CPEN Toxicology and Poisoning Emergencies Flashcards
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A 3-year-old presents after ingesting acetaminophen. Which antidote is indicated for acetaminophen toxicity?
Answer: N-acetylcysteine (NAC)
N-acetylcysteine (NAC) is the antidote for acetaminophen toxicity as it replenishes hepatic glutathione and prevents liver injury.
Which finding is most consistent with organophosphate poisoning in a pediatric patient?
Answer: Miosis, bradycardia, and excessive secretions
Organophosphate poisoning causes a cholinergic toxidrome characterized by miosis, bradycardia, bronchospasm, and excessive secretions (SLUDGE).
A toddler ingests iron tablets. Which early sign indicates iron toxicity?
Answer: Hematemesis and diarrhea
The early gastrointestinal phase of iron toxicity presents with vomiting, hematemesis, and diarrhea due to direct mucosal injury.
Which medication is the antidote for benzodiazepine overdose in a pediatric patient?
Answer: Flumazenil
Flumazenil competitively antagonizes benzodiazepine receptors and reverses CNS and respiratory depression caused by benzodiazepine overdose.
A 5-year-old ingested a button battery. What is the most serious immediate risk?
Answer: Esophageal perforation from electrical current and alkali burns
Button batteries lodged in the esophagus generate an electrical current and hydroxide ions that cause rapid, severe alkali burns and esophageal perforation.
Which intervention is the priority for a child presenting with suspected carbon monoxide poisoning?
Answer: Apply 100% oxygen via non-rebreather mask
High-flow 100% oxygen via non-rebreather mask displaces CO from hemoglobin and is the first-line treatment for carbon monoxide poisoning.