CPC CPC Organic Chemistry & Synthesis

Question 1

Which reaction mechanism involves the simultaneous breaking and forming of bonds in a single concerted step?

Accepted Answer

SN2

Answer

SN1

Answer

E1

Answer

E1cb

Question 2

In a Diels-Alder reaction, the diene must be in which conformation for the reaction to proceed?

Accepted Answer

s-cis

Answer

s-trans

Answer

anti-periplanar

Answer

gauche

Question 3

Which reagent is most commonly used to reduce an aldehyde to a primary alcohol?

Accepted Answer

NaBH4 or LiAlH4

Answer

NaBH4

Answer

LiAlH4

Answer

H2/Pt

Question 4

What is the product of ozonolysis of a terminal alkene followed by reductive workup (Me2S)?

Accepted Answer

Aldehyde and formaldehyde

Answer

Carboxylic acid and formaldehyde

Answer

Ketone and water

Answer

Diol

Question 5

Which of the following best describes a Grignard reagent acting as a nucleophile?

Accepted Answer

Carbon-metal bond donating electrons to an electrophile

Answer

Electrophile attacking a carbonyl

Answer

Proton donor to a base

Answer

Radical species reacting with oxygen

Question 6

Which protecting group is selectively removed under acidic conditions to reveal an alcohol?

Accepted Answer

THP (tetrahydropyranyl)

Answer

TBS (tert-butyldimethylsilyl)

Answer

Bn (benzyl)

Answer

Cbz