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CPC Adulteration & Specimen Validity Testing Flashcards

6 cards from real CPC practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

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  1. What is the acceptable pH range for a valid urine specimen in federal drug testing?

    Answer: 4.0 to 11.0

    Under 49 CFR Part 40, a urine specimen with a pH outside the range of 4.0 to 11.0 is reported as invalid due to incompatibility with normal human physiology.

  2. Why do some individuals attempt to add nitrites to a urine specimen before collection?

    Answer: Nitrites can destroy drug metabolites such as THC-COOH, potentially producing a false negative result

    Nitrites are an adulterant that can oxidize and destroy certain drug metabolites, particularly THC-COOH, to produce a falsely negative drug test result.

  3. How does a laboratory detect the presence of glutaraldehyde in a urine specimen?

    Answer: Through specific chemical validity tests that identify this adulterant by its reactivity or immunoassay interference

    Laboratories use specific chemical assays designed to detect glutaraldehyde and other commercial adulterant products, as standard drug tests alone cannot identify them.

  4. If a collector observes a donor attempt to pour a substance into the specimen cup, what must the collector do?

    Answer: Immediately stop the collection, document the observation on the CCF, and notify the DER

    Observed adulteration attempts must be documented immediately, the collection stopped, and the DER notified so that appropriate action, including a direct observation recollection, can be arranged.

  5. What is the consequence for a donor if their specimen is confirmed as adulterated under DOT regulations?

    Answer: The result is reported to the MRO and employer as a refusal to test, with the same consequences as a positive result

    An adulterated specimen confirmed by the laboratory is reported by the MRO as a refusal to test, which carries the same regulatory consequences as a verified positive result.

  6. Which federal agency's regulations govern specimen validity testing procedures for transportation industry drug testing programs?

    Answer: The Department of Transportation (DOT) under 49 CFR Part 40

    49 CFR Part 40, issued by the DOT, is the regulatory framework governing all aspects of federal workplace drug testing, including specimen validity testing.