CPC Organic Chemistry & Synthesis Flashcards
6 cards from real CPC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 CPC Organic Chemistry & Synthesis flashcards as text
Which synthesis method involves the condensation of an aldehyde with a compound bearing an active methylene group under basic or acidic conditions?
Answer: Aldol condensation
The aldol condensation joins an enolizable carbonyl compound to an aldehyde or ketone, followed by dehydration to form an α,β-unsaturated carbonyl product.
A chiral molecule that is NOT superimposable on its mirror image is called a(n):
Answer: Enantiomer pair member
A chiral molecule and its mirror image are non-superimposable and are called enantiomers, exhibiting identical physical properties except for rotation of plane-polarized light.
What is the role of the palladium catalyst in a Suzuki coupling reaction?
Answer: Undergoes oxidative addition, transmetalation, and reductive elimination cycle
In Suzuki coupling, Pd(0) undergoes oxidative addition into the aryl halide, then transmetalation with the boronic acid, followed by reductive elimination to form the biaryl product.
In retrosynthetic analysis, the disconnection approach is used to:
Answer: Work backward from product to identify viable synthetic precursors
Retrosynthetic analysis disconnects the target molecule into simpler precursors by identifying logical bond disconnections, working backward to commercially available starting materials.
Which reaction would you use to introduce a carboxyl group onto a terminal alkyne?
Answer: Carboxylation with CO2 after forming an acetylide anion
Deprotonation of a terminal alkyne with a strong base forms an acetylide anion, which reacts with CO2 to give a carboxylate (propiolic acid derivative) after acidification.
Which of the following describes the principle of microscopic reversibility in organic mechanisms?
Answer: The reverse reaction proceeds via the same transition states and intermediates as the forward reaction, in reverse
Microscopic reversibility states that under equilibrium conditions, the reverse reaction follows the exact same pathway as the forward reaction but in the opposite direction.