CPA Pesticide Toxicology and Mode of Action 2

Question 1

Neonicotinoid insecticides such as imidacloprid act primarily on which receptor in insects?

Accepted Answer

Nicotinic acetylcholine receptor

Answer

GABA-gated chloride channel

Answer

Ryanodine receptor

Answer

Voltage-gated sodium channel

Question 2

Which class of insecticides disrupts insect development by mimicking or interfering with juvenile hormone, preventing normal molting?

Accepted Answer

Insect growth regulators (IGRs)

Answer

Organochlorines

Answer

Pyrethroids

Answer

Carbamates

Question 3

A 'systemic' pesticide is one that:

Accepted Answer

Is absorbed by the plant and translocated throughout its tissues

Answer

Only kills pests through direct contact with the spray

Answer

Degrades rapidly in soil without residual activity

Answer

Only affects insects in the digestive tract

Question 4

What is the primary mode of action of organochlorine pesticides such as DDT?

Accepted Answer

Voltage-gated sodium channel disruption

Answer

Acetylcholinesterase inhibition

Answer

GABA receptor disruption

Answer

Chitin synthesis inhibition

Question 5

Which EPA toxicity category requires both the signal word 'DANGER' and the word 'POISON' printed on the pesticide label?

Accepted Answer

Category I

Answer

Category IV

Answer

Category III

Answer

Category II

Question 6

Bioaccumulation of pesticides in the food chain primarily occurs with compounds that are:

Accepted Answer

Lipophilic (fat-soluble) and environmentally persistent

Answer

Water soluble and rapidly degraded

Answer

Highly volatile and quickly lost to the atmosphere

Answer

Rapidly metabolized in animal tissues

Question 7

In pesticide toxicology, what does the term 'dermal absorption' specifically refer to?

Accepted Answer

Pesticide penetrating through the skin and entering the bloodstream

Answer

Pesticide entering the body through inhalation via the nose and lungs

Answer

Pesticide ingested through the mouth and absorbed in the gut

Answer

Pesticide entering the body through the eyes