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Pesticide Toxicology and Mode of Action Flashcards

7 cards from real CPA practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Diamide insecticides such as chlorantraniliprole control insects through which mode of action?

    Answer: Ryanodine receptor activation causing uncontrolled muscle contraction

    Diamides activate ryanodine receptors, triggering uncontrolled release of calcium from muscle cells, causing paralysis and death in insects.

  2. Which signal word appears on a pesticide label when the product falls into EPA Toxicity Category II (moderately toxic)?

    Answer: WARNING

    Category II products (oral LD50 of 50–500 mg/kg) require the signal word WARNING on the front panel of the label.

  3. Glyphosate herbicide kills plants by inhibiting which enzyme critical to amino acid biosynthesis?

    Answer: EPSPS (5-enolpyruvylshikimate-3-phosphate synthase)

    Glyphosate inhibits EPSPS in the shikimate pathway, blocking synthesis of aromatic amino acids essential for plant growth and survival.

  4. Chronic pesticide toxicity refers to adverse health effects that result from:

    Answer: Repeated or prolonged exposures over an extended period of time

    Chronic toxicity develops from repeated low-level exposures over months or years and may include cancer, reproductive effects, or organ damage.

  5. Hepatotoxic pesticides primarily target which organ in exposed individuals?

    Answer: Liver

    Hepatotoxic pesticides damage the liver (hepato = liver), which is the primary organ responsible for metabolizing and detoxifying pesticide compounds.

  6. The IRAC (Insecticide Resistance Action Committee) classification system groups insecticides according to their:

    Answer: Mode of action (target site)

    IRAC groups insecticides by mode of action so applicators can rotate between different groups to delay the development of insecticide resistance.

  7. In the context of pyrethroid insecticides, what does the term 'knockdown effect' describe?

    Answer: Rapid immobilization of insects shortly after exposure

    Pyrethroids are known for rapid knockdown — quick immobilization of flying or crawling insects — due to immediate disruption of sodium channel function in nerves.