COT Ophthalmic Pharmacology 2

Question 1

Which class of drugs used in glaucoma treatment works by reducing aqueous humor production through inhibition of carbonic anhydrase?

Accepted Answer

Carbonic anhydrase inhibitors

Answer

Carbonic anhydrase inhibitors such as dorzolamide and brinzolamide reduce aqueous humor production by inhibiting the enzyme carbonic anhydrase in the ciliary body.

Question 2

A patient taking pilocarpine for glaucoma reports difficulty driving at night. Which side effect best explains this complaint?

Accepted Answer

Miosis reducing pupil size in low light

Answer

Pilocarpine is a miotic agent that constricts the pupil, reducing the amount of light entering the eye and causing difficulty in dim lighting conditions.

Question 3

Which prostaglandin analog used to lower IOP is also FDA-approved for treating hypotrichosis of the eyelashes?

Accepted Answer

Bimatoprost

Answer

Bimatoprost (Lumigan) is used topically to lower IOP in glaucoma and is also marketed as Latisse for enhancing eyelash growth.

Question 4

Topical fluorescein sodium is most commonly used in the clinical setting to:

Accepted Answer

Stain corneal epithelial defects

Answer

Fluorescein sodium is a yellow-green dye that stains areas of devitalized or absent corneal epithelium, making defects visible under cobalt blue light.

Question 5

Which topical anesthetic is most commonly used in the ophthalmic office for procedures such as tonometry and foreign body removal?

Accepted Answer

Proparacaine

Answer

Proparacaine (0.5%) is the most widely used topical ophthalmic anesthetic due to its rapid onset, minimal stinging, and short duration of action.

COT - Certified Ophthalmic Technician Practice Test

COT - Certified Ophthalmic Technician Practice Test

COT Ophthalmic Pharmacology 2