COST Ocular Pathology & Disease Recognition 3

Question 1

The standard of care treatment for a medium-sized choroidal melanoma is:

Accepted Answer

Episcleral plaque brachytherapy

Answer

Systemic chemotherapy alone

Answer

Immediate enucleation

Answer

Topical antineoplastic therapy

Question 2

Retinoblastoma is associated with a mutation in which gene?

Accepted Answer

RB1 tumor suppressor gene on chromosome 13

Answer

BRCA1 on chromosome 17

Answer

TP53 on chromosome 17

Answer

VEGF on chromosome 6

Question 3

Optic neuritis as seen in multiple sclerosis characteristically presents with:

Accepted Answer

Acute unilateral vision loss with pain on eye movement

Answer

Gradual painless vision loss over several months

Answer

Bilateral simultaneous profound vision loss

Answer

Vision loss limited to the nasal visual field only

Question 4

Acute-onset post-surgical endophthalmitis is most commonly caused by which organism?

Accepted Answer

Coagulase-negative Staphylococci

Answer

Pseudomonas aeruginosa

Answer

Candida albicans

Answer

Streptococcus pyogenes

Question 5

Aqueous-deficient dry eye syndrome is most commonly caused by dysfunction of which structure?

Accepted Answer

Main lacrimal gland

Answer

Meibomian glands

Answer

Conjunctival goblet cells

Answer

Accessory lacrimal glands of Krause

Question 6

Preseptal cellulitis differs from orbital cellulitis in that it:

Accepted Answer

Is confined anterior to the orbital septum without proptosis or restricted motility

Answer

Involves infection posterior to the orbital septum

Answer

Requires emergent intravenous antibiotics in all cases

Answer

Commonly causes optic nerve compression and vision loss

Question 7

Central retinal artery occlusion (CRAO) presents with which characteristic funduscopic finding?

Accepted Answer

Cherry-red spot at the fovea with surrounding retinal whitening

Answer

Flame-shaped hemorrhages and disc edema

Answer

Disc neovascularization with vitreous hemorrhage

Answer

Drusen deposits with geographic atrophy of the RPE