COMSAE Dermatology and Integumentary System 3

Question 1

A 25-year-old woman notices well-circumscribed patches of hair loss on the scalp.
Examination reveals smooth scalp skin with 'exclamation point' hairs at the periphery of patches.
Which is the most likely diagnosis?

Accepted Answer

Alopecia areata

Answer

Androgenetic alopecia

Answer

Tinea capitis

Answer

Traction alopecia

Question 2

A 70-year-old presents with tense bullae on the trunk and extremities. The Nikolsky sign is negative. Direct immunofluorescence shows linear IgG and C3 deposits at the dermoepidermal junction. Which is the most likely diagnosis?

Accepted Answer

Bullous pemphigoid

Answer

Pemphigus vulgaris

Answer

Dermatitis herpetiformis

Answer

Epidermolysis bullosa acquisita

Question 3

A 30-year-old develops target-shaped lesions (concentric rings) on the palms and soles after a recent herpes simplex virus infection. There is no mucosal involvement. Which condition does this most likely represent?

Accepted Answer

Erythema multiforme minor

Answer

Stevens-Johnson syndrome

Answer

Toxic epidermal necrolysis

Answer

Fixed drug eruption

Question 4

A 45-year-old immigrant presents with intense nocturnal pruritus. Examination reveals burrows in the finger web spaces and erythematous papules on the wrists and genitalia. Which pathogen is responsible?

Accepted Answer

Sarcoptes scabiei

Answer

Pediculus humanus capitis

Answer

Demodex folliculorum

Answer

Phthirus pubis

Question 5

A 65-year-old presents with a dermatomal distribution of painful vesicles on an erythematous base on the right thorax. She had varicella as a child. Which antiviral should be initiated within 72 hours of onset?

Accepted Answer

Acyclovir

Answer

Oseltamivir

Answer

Ganciclovir

Answer

Amantadine

Question 6

A 22-year-old presents with well-defined depigmented macules on the dorsum of hands, around the mouth, and on the genitalia. Wood's lamp examination shows chalk-white fluorescence. The macules are asymptomatic. Which is the most likely diagnosis?

Accepted Answer

Vitiligo

Answer

Albinism

Answer

Pityriasis versicolor

Answer

Tinea corporis

Question 7

A 55-year-old diabetic presents with rapidly spreading erythema, warmth, swelling, and tenderness of the lower leg with a distinct raised, palpable border and fever. Which condition most likely explains the palpable, sharply demarcated border?

Accepted Answer

Erysipelas involving the superficial dermis and lymphatics

Answer

Cellulitis involving the deep dermis and subcutaneous tissue

Answer

Necrotizing fasciitis involving fascia and muscle

Answer

Folliculitis involving hair follicles