COCN COCN Oncologic Emergencies 3

Question 1

When preparing a neutropenic fever patient for empiric antibiotic therapy, what is the target time from fever detection to first antibiotic dose?

Accepted Answer

Within 1 hour

Answer

Current oncology guidelines recommend administering empiric broad-spectrum antibiotics within 60 minutes of fever identification in neutropenic patients.

Question 2

Which imaging modality is preferred for emergency evaluation of suspected malignant spinal cord compression?

Accepted Answer

MRI of the entire spine

Answer

MRI of the entire spine is the gold standard for identifying the level and extent of epidural cord compression.

Question 3

A patient with SCLC is admitted with sudden agitation, confusion, and a serum sodium of 118 mEq/L. The initial treatment is:

Accepted Answer

Fluid restriction with careful slow sodium correction

Answer

Fluid restriction is first-line for SIADH; sodium must be corrected slowly (≤8–10 mEq/L/day) to prevent osmotic demyelination syndrome.

Question 4

Which sign is associated with hypocalcemia seen in tumor lysis syndrome when a blood pressure cuff causes carpal spasm?

Accepted Answer

Trousseau sign

Answer

Trousseau sign is carpal spasm elicited by inflating a BP cuff above systolic pressure, indicating hypocalcemia-induced neuromuscular irritability.

Question 5

In the management of DIC in an oncology patient, which blood product replaces clotting factors V and VIII most effectively?

Accepted Answer

Fresh frozen plasma (FFP)

Answer

FFP contains all clotting factors and is the primary product for replacing factor deficiencies in DIC.

COCN Test Practice Test

COCN Test Practice Test

COCN COCN Oncologic Emergencies 3