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Clinical Chemistry Flashcards

7 cards from real CMT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Clinical Chemistry flashcards as text
  1. Two consecutive control results exceed +2 SD on the same side of the mean. This violates which Westgard rule, and what error does it indicate?

    Answer: 2-2s; systematic error

    2-2s rejects a run when two consecutive controls exceed 2 SD on the same side, which signals systematic bias.

  2. According to Beer's law, absorbance is:

    Answer: Directly proportional to concentration

    A = abc, so absorbance increases linearly with concentration at a fixed path length.

  3. The Jaffe method for creatinine uses which reagent?

    Answer: Alkaline picrate

    Creatinine reacts with picrate in alkaline solution to form a red-orange complex.

  4. Increased conjugated bilirubin, positive urine bilirubin, and decreased urine urobilinogen most strongly suggest:

    Answer: Biliary obstruction

    Blockage stops bilirubin reaching the gut, so urobilinogen falls while water-soluble conjugated bilirubin spills into urine.

  5. Which handling requirement is most critical for a serum bilirubin specimen?

    Answer: Protect from light

    Light breaks down bilirubin and causes falsely low results.

  6. For a plasma ammonia level, the specimen should be:

    Answer: Placed on ice and analyzed promptly

    Red cell metabolism and deamination in vitro raise ammonia quickly, so chilling and fast testing are essential.

  7. Urine creatinine 100 mg/dL, plasma creatinine 1.0 mg/dL, 24-hour urine volume 1440 mL. What is the creatinine clearance?

    Answer: 100 mL/min

    1440 mL/day is 1 mL/min, so clearance = (100 × 1)/1.0 = 100 mL/min.