CMLA Hematology Basics 3

Question 1

Which type of anemia is characterized by hypersegmented neutrophils on a peripheral blood smear?

Accepted Answer

Megaloblastic anemia

Answer

Megaloblastic anemia (due to B12 or folate deficiency) causes hypersegmented neutrophils with 5 or more lobes.

Question 2

The Wintrobe hematocrit method uses a tube that is centrifuged for how long?

Accepted Answer

30 minutes at 3,000 rpm

Answer

The Wintrobe method requires centrifugation at 3,000 rpm for 30 minutes to separate blood components.

Question 3

Which cell type is elevated in allergic reactions and parasitic infections?

Accepted Answer

Eosinophil

Answer

Eosinophilia occurs in allergic conditions and parasitic infections due to their role in these immune responses.

Question 4

What does a left shift in the WBC differential indicate?

Accepted Answer

Increased immature neutrophils (bands)

Answer

A left shift indicates the presence of increased band neutrophils or earlier precursors, often indicating severe bacterial infection.

Question 5

Which hemoglobin type is predominant in normal adults?

Accepted Answer

Hemoglobin A

Answer

Hemoglobin A (alpha2beta2) makes up approximately 95-98% of normal adult hemoglobin.

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