CMLA Hematology Basics 2

Question 1

Which white blood cell is the first to respond to a bacterial infection?

Accepted Answer

Neutrophil

Answer

Neutrophils are the first responders to bacterial infection due to their rapid migration and phagocytic ability.

Question 2

What is the normal lifespan of a red blood cell in circulation?

Accepted Answer

120 days

Answer

Red blood cells have a normal lifespan of approximately 120 days before being removed by the spleen.

Question 3

Which organelle is absent in mature red blood cells?

Accepted Answer

Nucleus

Answer

Mature red blood cells lack a nucleus, which was extruded during the final stages of erythropoiesis.

Question 4

The MCHC (Mean Corpuscular Hemoglobin Concentration) is calculated by dividing:

Accepted Answer

Hemoglobin by hematocrit × 100

Answer

MCHC is calculated as (Hemoglobin / Hematocrit) × 100, expressing average hemoglobin concentration per unit volume of red cells.

Question 5

A patient's blood smear shows target cells (codocytes). Which condition is MOST associated with this finding?

Accepted Answer

Hemoglobin C disease

Answer

Target cells are classically associated with hemoglobin C disease, thalassemia, and liver disease.

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