CMC CMC Cardiac Pharmacology & Medications

Question 1

Which drug class is first-line for reducing ventricular rate in atrial fibrillation?

Accepted Answer

Beta-blockers

Answer

Beta-blockers reduce ventricular rate by blocking sympathetic stimulation of the AV node.

Question 2

ACE inhibitors lower blood pressure primarily by blocking which enzyme?

Accepted Answer

Angiotensin-converting enzyme

Answer

ACE inhibitors block angiotensin-converting enzyme, preventing formation of angiotensin II and lowering blood pressure.

Question 3

Which anticoagulant requires regular INR monitoring due to its narrow therapeutic window?

Accepted Answer

Warfarin

Answer

Warfarin requires INR monitoring because of its variable metabolism and narrow therapeutic range.

Question 4

Digoxin is used in cardiac care primarily for which two conditions?

Accepted Answer

Atrial fibrillation and heart failure

Answer

Digoxin controls ventricular rate in atrial fibrillation and increases contractility in heart failure via Na+/K+-ATPase inhibition.

Question 5

Statins reduce cardiovascular risk by inhibiting which enzyme in the cholesterol synthesis pathway?

Accepted Answer

HMG-CoA reductase

Answer

Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol biosynthesis, lowering LDL.

CMC - Cardiac Medicine Certification Practice Test