CLT Treatment Protocols & Procedures 2

Question 1

A patient on warfarin therapy has an INR of 5.8 with no active bleeding. What is the most appropriate initial management?

Accepted Answer

Hold warfarin and monitor closely

Answer

For supratherapeutic INR without bleeding, holding warfarin and monitoring is the first-line approach before considering vitamin K.

Question 2

Which blood component is the MOST appropriate for a patient with isolated factor VIII deficiency (hemophilia A)?

Accepted Answer

Cryoprecipitate

Answer

Cryoprecipitate is rich in factor VIII, fibrinogen, von Willebrand factor, and factor XIII, making it preferred for hemophilia A treatment.

Question 3

A patient requires a blood transfusion but has a known history of febrile non-hemolytic transfusion reactions. What modification to the transfusion should be made?

Accepted Answer

Use leukoreduced blood products

Answer

Leukoreduction removes white blood cells that cause febrile non-hemolytic reactions by releasing cytokines during storage.

Question 4

In disseminated intravascular coagulation (DIC), which laboratory finding combination is most characteristic?

Accepted Answer

Prolonged PT/PTT, low fibrinogen, elevated D-dimer

Answer

DIC is characterized by consumption of clotting factors (prolonged PT/PTT), fibrinogen depletion, low platelets, and elevated D-dimer from fibrin degradation.

Question 5

Which electrolyte imbalance is most commonly associated with massive blood transfusion and requires monitoring?

Accepted Answer

Hypocalcemia

Answer

Citrate in stored blood products chelates calcium, causing hypocalcemia during massive transfusion, especially when the liver cannot metabolize citrate fast enough.

(CLT) Clinical Laboratory Technologist Certification Practice Test

(CLT) Clinical Laboratory Technologist Certification Practice Test

CLT Treatment Protocols & Procedures 2