CLT Clinical Chemistry & Biochemical Analysis 2

Question 1

Which of the following best describes the Beer-Lambert Law as applied to spectrophotometry in clinical chemistry?

Accepted Answer

Absorbance is directly proportional to concentration and path length

Answer

Absorbance is inversely proportional to concentration

Answer

Transmittance is directly proportional to concentration

Answer

Absorbance is independent of wavelength

Question 2

Hemoglobin A1c (HbA1c) reflects average blood glucose control over approximately what time period?

Accepted Answer

8–12 weeks

Answer

2–4 weeks

Answer

4–6 weeks

Answer

6–12 months

Question 3

Troponin I or T elevation in a patient with chest pain is most indicative of which condition?

Accepted Answer

Acute myocardial infarction

Answer

Pulmonary embolism

Answer

Acute pancreatitis

Answer

Renal failure

Question 4

Which method is considered the reference (gold standard) for measuring serum cholesterol?

Accepted Answer

Abell-Kendall method

Answer

Enzymatic colorimetric method

Answer

Liebermann-Burchard reaction

Answer

Ion-selective electrode method

Question 5

An arterial blood gas result shows pH 7.28, pCO2 55 mmHg, and HCO3 26 mEq/L. What is the primary acid-base disturbance?

Accepted Answer

Respiratory acidosis

Answer

Metabolic acidosis

Answer

Metabolic alkalosis

Answer

Respiratory alkalosis

Question 6

What is the primary purpose of running a calibration curve in clinical chemistry assays?

Accepted Answer

To establish the relationship between signal and analyte concentration

Answer

To detect instrument malfunctions

Answer

To ensure reagent stability

Answer

To verify specimen integrity

Question 7

Elevated serum amylase and lipase are most characteristic of which condition?

Accepted Answer

Acute pancreatitis

Answer

Hepatitis

Answer

Myocardial infarction

Answer

Renal insufficiency