Wound Healing & Tissue Repair Flashcards
7 cards from real CLT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Wound Healing & Tissue Repair flashcards as text
What are the four primary phases of wound healing in the correct sequential order?
Answer: Hemostasis, inflammation, proliferation, remodeling
Wound healing occurs in four sequential phases: hemostasis (clotting), inflammation (immune response), proliferation (tissue building), and remodeling (scar maturation).
Which photoacceptor in cells is primarily responsible for absorbing red and near-infrared light to promote wound healing?
Answer: Cytochrome c oxidase
Cytochrome c oxidase in the mitochondrial respiratory chain is the primary photoacceptor for red and near-infrared light, triggering increased ATP production that supports wound healing.
During which phase of wound healing does collagen synthesis by fibroblasts primarily occur?
Answer: Proliferative phase
The proliferative phase is characterized by fibroblast activity, collagen synthesis, angiogenesis, and granulation tissue formation to fill the wound.
What wavelength range is most commonly used in photobiomodulation for promoting wound healing?
Answer: 600–1100 nm (red to near-infrared)
The therapeutic window of 600–1100 nm (red to near-infrared) is most effective for wound healing because these wavelengths penetrate tissue and stimulate cellular repair mechanisms.
Which growth factor, upregulated by light therapy, plays a key role in angiogenesis during wound healing?
Answer: Vascular endothelial growth factor (VEGF)
VEGF is a primary mediator of angiogenesis (new blood vessel formation), and photobiomodulation has been shown to upregulate VEGF expression, enhancing blood supply to healing wounds.
Chronic wounds are often characterized by which of the following?
Answer: Prolonged inflammatory phase and impaired proliferation
Chronic wounds are stuck in a prolonged inflammatory phase with elevated proteases, impaired fibroblast function, and failure to progress to the proliferative phase.
How does photobiomodulation reduce inflammation in early wound healing without completely suppressing the immune response?
Answer: By modulating reactive oxygen species and promoting anti-inflammatory mediators
Photobiomodulation modulates ROS levels and promotes anti-inflammatory mediators like IL-10, reducing excessive inflammation while preserving the necessary immune response for healing.