CLT CLT Hematology & Blood Analysis 3

Question 1

Which condition is characterized by the presence of Howell-Jolly bodies on a peripheral blood smear?

Accepted Answer

Sickle cell disease or post-splenectomy

Answer

Viral hepatitis

Answer

Chronic kidney disease

Answer

Polycythemia vera

Question 2

What is the principle behind the automated cell counter's impedance method for counting blood cells?

Accepted Answer

Cells disrupt electrical current as they pass through an aperture

Answer

Cells scatter laser light in proportion to their size

Answer

Cells absorb specific fluorescent dyes

Answer

Cells sediment at different rates in a centrifuge

Question 3

A patient presents with a prolonged aPTT but a normal PT. Which coagulation factor deficiency is most consistent with this result?

Accepted Answer

Factor VIII (Hemophilia A)

Answer

Factor VII

Answer

Factor II (Prothrombin)

Answer

Fibrinogen

Question 4

Hypersegmented neutrophils (>5 lobes) on a blood smear are a classic finding in which type of anemia?

Accepted Answer

Megaloblastic anemia (B12 or folate deficiency)

Answer

Iron deficiency anemia

Answer

Hemolytic anemia

Answer

Aplastic anemia

Question 5

Which parameter in a CBC directly reflects the variation in red blood cell size?

Accepted Answer

RDW (Red Cell Distribution Width)

Answer

MCH

Answer

MCHC

Answer

Hematocrit

Question 6

During a manual differential count, a technologist observes large cells with prominent nucleoli and scant cytoplasm. These are most consistent with which cells?

Accepted Answer

Blasts (immature cells)

Answer

Mature lymphocytes

Answer

Neutrophil bands

Answer

Eosinophils