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Food Sensitivities & Immunology Basics Flashcards

7 cards from real CLT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. The innate immune system responds to food antigens non-specifically, while the adaptive immune system is characterized by:

    Answer: Antigen specificity and immunological memory

    The adaptive immune system generates antigen-specific lymphocytes and memory cells, enabling faster and stronger responses upon repeated antigen exposure.

  2. In the LEAP protocol, the 'systematic food reintroduction' phase serves which primary purpose?

    Answer: To add back foods in a controlled sequence to identify remaining triggers and expand dietary variety

    Systematic reintroduction in Phase 2 allows the LEAP therapist and client to identify additional triggers and gradually broaden the diet while monitoring symptom responses.

  3. The complement system is activated in food sensitivity primarily via the:

    Answer: Classical pathway triggered by IgG/IgM immune complexes

    In Type III hypersensitivity food reactions, IgG and IgM antibodies form immune complexes with food antigens that activate complement via the classical pathway.

  4. Which dietary pattern is most commonly associated with reducing overall mediator burden and supporting the LEAP dietary goals?

    Answer: Anti-inflammatory diet emphasizing whole foods and avoiding individually reactive items

    An anti-inflammatory whole-foods diet tailored to individual MRT results minimizes mediator release and supports symptom resolution in LEAP therapy.

  5. Platelet-activating factor (PAF) is a potent lipid mediator released in food sensitivity reactions that contributes to:

    Answer: Bronchoconstriction, increased vascular permeability, and platelet aggregation

    PAF mediates multiple inflammatory effects including airway constriction, vascular leakage, and platelet clumping, amplifying food sensitivity symptoms.

  6. Regulatory T cells (Tregs) play a critical role in food tolerance by:

    Answer: Suppressing excessive immune responses and promoting tolerance via IL-10 and TGF-β

    Tregs secrete suppressive cytokines IL-10 and TGF-β that downregulate Th1/Th2 responses and are essential for maintaining oral tolerance to food antigens.

  7. When evaluating a new LEAP client, which clinical history finding would most strongly suggest a non-IgE-mediated food sensitivity rather than a classic food allergy?

    Answer: Chronic migraines and joint stiffness improving on weekends when diet changes

    Chronic, diffuse symptoms with a delayed pattern and lifestyle correlation (diet changing on weekends) are hallmarks of non-IgE food sensitivity, not anaphylaxis-type food allergy.