CLS CLS Hematology and Coagulation 1 — Questions and Answers
Question 1: Which blood cell type is primarily responsible for oxygen transport?
- Leukocytes
- Thrombocytes
- Erythrocytes (Correct answer)
- Monocytes
Correct answer: Erythrocytes
Erythrocytes contain hemoglobin, which binds and carries oxygen to tissues throughout the body.
Question 2: What is the normal reference range for hemoglobin in adult males?
- 8–10 g/dL
- 12–14 g/dL
- 13.5–17.5 g/dL (Correct answer)
- 18–22 g/dL
Correct answer: 13.5–17.5 g/dL
The normal hemoglobin range for adult males is 13.5–17.5 g/dL, higher than the female reference range.
Question 3: Which coagulation pathway is initiated by tissue factor (Factor III)?
- Intrinsic pathway
- Extrinsic pathway (Correct answer)
- Common pathway
- Fibrinolytic pathway
Correct answer: Extrinsic pathway
The extrinsic pathway is activated by tissue factor released from damaged tissue, which complexes with Factor VII.
Question 4: The Prothrombin Time (PT) test primarily evaluates which coagulation pathway(s)?
- Intrinsic pathway only
- Extrinsic and common pathways (Correct answer)
- Platelet aggregation
- Fibrinolytic pathway
Correct answer: Extrinsic and common pathways
PT evaluates the extrinsic and common pathways by measuring activity of Factors II, V, VII, X, and fibrinogen.
Question 5: Which white blood cell type is normally most numerous on a peripheral blood smear?
- Lymphocytes
- Monocytes
- Neutrophils (Correct answer)
- Eosinophils
Correct answer: Neutrophils
Neutrophils typically comprise 50–70% of the total white blood cell count in healthy adults.
Question 6: What does Mean Platelet Volume (MPV) measure on a CBC?
- Average red blood cell volume
- Average platelet size (Correct answer)
- Total platelet count
- Platelet aggregation activity
Correct answer: Average platelet size
MPV measures the average size of platelets and reflects platelet production and turnover.
CLS CLS Hematology and Coagulation 1
Which blood cell type is primarily responsible for oxygen transport?