Pharmacology & Medication Management Flashcards
7 cards from real CHS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology & Medication Management flashcards as text
Doxorubicin (Adriamycin) is considered a relative contraindication for HBO therapy because it:
Answer: Potentiates cardiotoxicity under high oxygen partial pressures
Doxorubicin has known cardiotoxic effects, and high oxygen partial pressures may potentiate cardiac oxidative damage in patients receiving this agent.
When managing a patient on warfarin undergoing HBO therapy for chronic wound care, the clinician should be aware that HBO may:
Answer: Potentiate anticoagulant effects by increasing platelet sensitivity
HBO therapy has been shown to potentiate the anticoagulant effects of warfarin, requiring closer INR monitoring in patients on long-term HBO courses.
Which medication used for carbon monoxide poisoning acts synergistically with HBO by increasing CO elimination from cytochrome oxidase?
Answer: Hydroxocobalamin
Hydroxocobalamin binds cyanide and works alongside HBO in combined CO/cyanide poisoning (as in smoke inhalation), while HBO displaces CO from hemoglobin and cytochrome oxidase.
Nitroglycerin patches worn by a patient during HBO should be managed how?
Answer: Removed before treatment to prevent unpredictable absorption and fire risk
Nitroglycerin patches should be removed before HBO sessions because pressure alters transdermal absorption rates and the adhesive base may pose a fire hazard.
A hyperbaric patient on theophylline (bronchodilator) requires careful monitoring because HBO may:
Answer: Lower the seizure threshold in combination with theophylline's CNS effects
Theophylline lowers the seizure threshold via adenosine antagonism, and this effect is additive with CNS oxygen toxicity risk in HBO therapy.
Bleomycin chemotherapy is considered a strong contraindication for HBO because it causes:
Answer: Cumulative pulmonary fibrosis worsened by high-pressure oxygen
Bleomycin causes pulmonary fibrosis that is dramatically worsened by high inspired oxygen fractions, making HBO potentially fatal in patients with bleomycin exposure.
When a patient requires IV medication during a multiplace HBO treatment, the drug delivery system must be evaluated for:
Answer: Pressure effects on flow rates and air bubbles in IV lines
Pressure increases gas solubility, but bubbles trapped in IV tubing can compress and later expand, causing flow rate inaccuracies and potential air embolism risk on decompression.