Pharmacology & Medication Management Flashcards
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Read the first 7 Pharmacology & Medication Management flashcards as text
Which medication class is contraindicated in hyperbaric oxygen therapy due to its ability to lower the seizure threshold in an oxygen-enriched environment?
Answer: Fluoroquinolone antibiotics
Fluoroquinolones lower the seizure threshold and should be withheld before HBO sessions due to increased CNS oxygen toxicity risk.
Disulfiram (Antabuse) is a concern in HBO therapy primarily because it:
Answer: Inhibits superoxide dismutase and worsens oxidative stress
Disulfiram inhibits superoxide dismutase, impairing the patient's ability to detoxify reactive oxygen species generated during HBO therapy.
A patient on insulin pump therapy is scheduled for HBO. What is the recommended management of the insulin pump during treatment?
Answer: Suspend the pump and remove it from the chamber
Insulin pumps contain electronic components and gas-filled reservoirs that are incompatible with hyperbaric pressure and must be removed before chamber entry.
Cisplatin (a chemotherapy agent) in combination with HBO therapy primarily raises concern for:
Answer: Enhanced pulmonary oxygen toxicity
Cisplatin sensitizes lung tissue to oxygen toxicity, increasing the risk of pulmonary oxygen toxicity when combined with HBO therapy.
Which topical agent is absolutely prohibited inside a hyperbaric chamber due to fire hazard?
Answer: Petroleum-based ointments
Petroleum-based products are highly flammable and absolutely contraindicated inside hyperbaric chambers because oxygen-enriched environments dramatically lower ignition thresholds.
A patient receiving methotrexate for rheumatoid arthritis is referred for HBO. The primary concern regarding this medication is:
Answer: It increases pulmonary oxygen toxicity risk
Methotrexate can cause pulmonary toxicity, and combined with high-pressure oxygen, the risk of pulmonary oxygen toxicity is significantly increased.
Epinephrine auto-injectors (EpiPens) brought into a hyperbaric chamber by a patient pose a risk because:
Answer: The pressurized auto-injector device may malfunction or discharge
Pressurized auto-injector devices can malfunction, accidentally discharge, or rupture under hyperbaric conditions, posing both an injection hazard and a fire risk.