Pharmacology & Medication Management Flashcards
7 cards from real CHS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology & Medication Management flashcards as text
Vitamin E supplementation prior to HBO therapy has been studied for its role in:
Answer: Reducing pulmonary oxygen toxicity through antioxidant mechanisms
Vitamin E is a fat-soluble antioxidant studied for its potential to attenuate pulmonary oxygen toxicity by scavenging reactive oxygen species during HBO courses.
A patient taking tramadol is referred for HBO therapy. The specific concern regarding this opioid analgesic is:
Answer: Tramadol lowers seizure threshold, compounding CNS oxygen toxicity risk
Tramadol is known to lower the seizure threshold, which is additive to the CNS oxygen toxicity risk already present during HBO treatments at depth.
Sulfamylon (mafenide acetate) is commonly used in wound care for burn patients in HBO. The primary pharmacological concern is:
Answer: It is a carbonic anhydrase inhibitor that can cause metabolic acidosis
Mafenide acetate inhibits carbonic anhydrase, potentially causing metabolic acidosis, which must be monitored during intensive burn wound care combined with HBO.
Which sedation agent is most appropriate for use in a monoplace hyperbaric chamber when a patient cannot tolerate the treatment without pharmacological assistance?
Answer: Oral benzodiazepine (e.g., lorazepam) administered 30 minutes before treatment
Oral benzodiazepines given before chamber entry are the safest anxiolytic approach for monoplace HBO because they avoid the need for electronic infusion devices inside the chamber.
The pharmacokinetics of inhaled anesthetic agents (e.g., isoflurane) are altered in hyperbaric environments primarily because:
Answer: Increased partial pressures reduce the MAC required for anesthesia
The minimum alveolar concentration (MAC) of inhaled anesthetics decreases predictably as ambient pressure increases, following Henry's Law principles regarding partial pressures.
Erythropoietin (EPO) use in HBO therapy has been investigated to:
Answer: Stimulate red blood cell production to enhance long-term tissue oxygenation after HBO courses
EPO stimulates erythropoiesis and has been studied as an adjunct to HBO to enhance sustained oxygen delivery to ischemic tissues beyond the treatment window.
A patient with type 1 diabetes requires blood glucose monitoring during a 90-minute HBO treatment. The preferred method is:
Answer: Fingerstick glucose check via glucometer passed through the chamber medical lock
Electronic CGM sensors are not approved for hyperbaric use, so glucose samples should be obtained via the medical lock and tested outside the chamber.