CFS CFS Pathophysiology and Research

Question 1

Which body system is believed to play a central role in CFS pathophysiology according to current research?

Accepted Answer

Immune system dysregulation

Answer

Current research strongly implicates immune system dysregulation, including abnormal cytokine profiles and immune activation, in the pathophysiology of CFS.

Question 2

What is the 'two-hit hypothesis' sometimes proposed for CFS?

Accepted Answer

An initial trigger (e.g., infection) combined with a second factor perpetuates the illness

Answer

The two-hit hypothesis suggests CFS may result from an initial trigger like an infection combined with a secondary factor that prevents normal recovery.

Question 3

What does research suggest about mitochondrial function in CFS patients?

Accepted Answer

Evidence suggests impaired mitochondrial energy production in some CFS patients

Answer

Some CFS research has found evidence of impaired mitochondrial function, potentially contributing to the profound energy deficits experienced by patients.

Question 4

Which biomarker abnormality has been reported in some CFS research studies?

Accepted Answer

Reduced natural killer (NK) cell cytotoxic activity

Answer

Reduced natural killer cell cytotoxic activity has been one of the more consistently reported immune abnormalities in CFS research literature.

Question 5

What does the term 'neuroimmune' mean in the context of CFS?

Accepted Answer

Involving both the nervous system and the immune system

Answer

'Neuroimmune' describes conditions involving interactions between the nervous system and immune system, which is why CFS is sometimes classified as a neuroimmune disease.

CFS - Chronic Fatigue Syndrome Practice Test

CFS - Chronic Fatigue Syndrome Practice Test

CFS CFS Pathophysiology and Research